NASA's SpaceX Crew-10 Returns Safely After Completing Dozens of ISS National Lab-Sponsored Investigations

Astronauts wrap up mission after supporting research that could lead to new cancer treatments, more lifelike robotics, space debris removal, and more

KENNEDY SPACE CENTER, Fla., Aug. 11, 2025 -- After nearly six months onboard the International Space Station (ISS), the four astronauts of NASA's SpaceX Crew-10 mission have safely returned to Earth. This weekend's splashdown off the coast of California concludes a long-duration science expedition that supported dozens of investigations sponsored by the ISS National Laboratory^®.

NASA astronauts Anne McClain and Nichole Ayers, Japan Aerospace Exploration Agency (JAXA) astronaut Takuya Onishi, and Roscosmos cosmonaut Kirill Peskov played a vital role in advancing science in space, contributing to biomedical research, physical and materials sciences, technology demonstrations, and student-led experiments. Their work helped push the boundaries of discovery in low Earth orbit to benefit life on Earth and support a sustainable and robust space economy.

ISS National Lab-sponsored projects the crew worked on during their mission include the following:

• A project from the University of Connecticut and Eascra Biotech, in partnership with Axiom Space, is using microgravity to improve the production of Janus base nanomaterials, which could be used to treat diseases like osteoarthritis and cancer. This project builds on previous ISS investigations and is funded through NASA's In-Space Production Applications program.
• Multiple projects were funded by the U.S. National Science Foundation, which has a long-standing partnership with the ISS National Lab to advance fundamental research on the orbiting laboratory.
• Rensselaer Polytechnic Institute, in partnership with Tec-Masters, is building on previous research to better understand why protein clumping occurs during pharmaceutical manufacturing—a significant challenge in the industry.
• Researchers from the University of California, Santa Barbara, in collaboration with Redwire Space Technologies, are studying a liquid separation phenomenon that could be used to create materials for more lifelike robotics.
• ELVIS may enhance the search for life beyond Earth. Portland State University, in collaboration with NASA's Jet Propulsion Laboratory in Southern California and Teledyne Brown Engineering, Inc., tested a new holographic microscope—the Extant Life Volumetric Imaging System (ELVIS)—that could allow scientists to study the adaptability of life under extreme conditions.
• Kall Morris Inc, in partnership with Voyager Technologies, leveraged the Astrobee free-flying robots on the space station to validate its REACCH system, which uses tentacle-looking arms with gecko-like adhesive pads to capture floating space debris. REACCH could help protect critical in-orbit infrastructure for Internet communications, weather prediction, GPS, and more.

The ISS National Lab is proud to have partnered with NASA and international collaborators to enable this impactful space-based research for the benefit of humanity. The return of NASA's SpaceX Crew-10 mission marks the successful completion of another science expedition in the ongoing effort to leverage space as an innovation platform.

To learn more about the science supported by the astronauts during this mission, visit our launch page.

Download a high-resolution image for this release: Crew-10 Return

About the International Space Station (ISS) National Laboratory:
The International Space Station (ISS) is a one-of-a-kind laboratory that enables research and technology development not possible on Earth. As a public service enterprise, the ISS National Laboratory^® allows researchers to leverage this multiuser facility to improve quality of life on Earth, mature space-based business models, advance science literacy in the future workforce, and expand a sustainable and scalable market in low Earth orbit. Through this orbiting national laboratory, research resources on the ISS are available to support non-NASA science, technology, and education initiatives from U.S. government agencies, academic institutions, and the private sector. The Center for the Advancement of Science in Space^® (CASIS^®) manages the ISS National Lab, under Cooperative Agreement with NASA, facilitating access to its permanent microgravity research environment, a powerful vantage point in low Earth orbit, and the extreme and varied conditions of space. To learn more about the ISS National Lab, visit our website.

As a 501(c)(3) nonprofit organization, CASIS accepts corporate and individual donations to help advance science in space for the benefit of humanity. For more information, visit our donations page.

SOURCE International Space Station National Lab