NBC's Today Show Features Signalife's ECG Technology

'Modern Medical Miracles' segment features Signalife with the Cleveland Clinic and Champ Car Medical Safety Program

GREENVILLE, S.C., Nov. 30 -- Budimir Drakulic, Chief Technology Officer and inventor of Signalife's revolutionary ECG technology has been working with the world famous Cleveland Clinic physicians and Champ Car Medical Director Dr. Chris Pinderski for more than a year. The study utilizes Signalife's ECG technology in a Hi-Tech Heart Monitor. The device, which is a vest, is worn under the driver's suit while racing of speeds greater than 200 miles per hour.

Signalife's superior technology was chosen for the study due to the clarity of the signal in harsh environments. The heart monitor has shown clinical value to physicians in determining what is going on with the Champ Car drivers during testing and races. Pam Bunes, President and CEO of Signalife states, "We were thrilled to have been selected for this study and look forward to future opportunities to apply our technology in the ambulatory heart monitoring industry."

To view this segment on NBC's Today Show click on the following link, http://www.msnbc.msn.com/id/3032633/

About Signalife

Signalife, Inc. is a medical device company focused on the detection of cardiovascular disease through continuous ECG signal monitoring. The company's goal is to become the premier provider of cardiovascular disease monitoring products. Signalife uses its patented signal technology to design and develop medical devices that simplify and reduce the costs of diagnostic testing and patient monitoring in an ambulatory environment. Signalife's revolutionary FDA-approved electrocardiograph (ECG) monitoring system called Fidelity 100 allows for the recording of a quality ECG signal from ambulatory cardiac patients. The Fidelity 100 will address a portion of the $400 billion cardiac disease market. Signalife, Inc. is traded on the American Stock Exchange under the symbol SGN. The company's website is available at: http://www.signalife.com/

Caution Regarding Forward-Looking Statements

Statements in this release that are not strictly historical are "forward- looking" statements. Forward-looking statements involve known and unknown risks, which may cause Signalife, Inc. results in the future to differ materially from expected results. Factors which could cause or contribute to such differences include, but are not limited to, failure to complete the development and introduction of new products or services, failure to obtain federal or state regulatory approval governing medical devices, monitoring and other related services or products, inability to obtain physician, patient or insurance acceptance of Signalife's products or services, adverse equity market conditions and declines in the value of Signalife's common stock, and the unavailability of financing to complete management's plans and objectives. These risks are qualified by cautionary language and risk factors set forth and to be further described in Signalife's filings with the Securities and Exchange Commission.